Registration Dossier
Registration Dossier
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EC number: 279-420-3 | CAS number: 80206-82-2
Epidemiological data
Administrative data
- Endpoint:
- epidemiological data
- Type of information:
- other: published data
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
Materials and methods
- Study type:
- cohort study (retrospective)
- Endpoint addressed:
- skin irritation / corrosion
- skin sensitisation
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Method other: allergic skin reaction in man
Method: In a retrospective survey of allergic reactions to cosmetics, data on 475 patients with contact allergy to cosmetic ingredients were collected in 5 European dermatology centres. - GLP compliance:
- not specified
Test material
- Reference substance name:
- Hexadecan-1-ol
- EC Number:
- 253-149-0
- EC Name:
- Hexadecan-1-ol
- Cas Number:
- 36653-82-4
- Molecular formula:
- C16H34O
- IUPAC Name:
- hexadecan-1-ol
- Details on test material:
- - Name of test material (as cited in study report):Cetyl alcohol
Constituent 1
Method
- Type of population:
- general
- Ethical approval:
- not specified
- Details on study design:
- In a retrospective survey of allergic reactions to cosmetics, data on 475 patients with contact allergy to cosmetic ingredients were collected in 5 European dermatology centres. The observations were made over a 4 month period in 1996. A positive response to cetyl alcohol was obtained in only 3/475 patients.
- Exposure assessment:
- estimated
Results and discussion
- Results:
- The observations were made over a 4 month period in 1996. A positive response to cetyl alcohol was obtained in only 3/475 patients.
Applicant's summary and conclusion
- Conclusions:
- In a retrospective survey of allergic reactions to cosmetics, data on 475 patients with contact allergy to cosmetic ingredients were collected in 5 European dermatology centres. The observations were made over a 4 month period in 1996. A positive response to cetyl alcohol was obtained in only 3/475 patients.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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