Registration Dossier
Registration Dossier
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EC number: 939-200-6 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Acute studies conducted using sodium isobutyrate solution (reaction mass of lithium 3-hydroxy-2,2,4-trimethylpentanoate and lithium isobutyrate and sodium 3-hydroxy-2,2,4-trimethylpentanoate and sodium isobutyrate) are available for fish, Daphnia magna, algae and activated sludge microorganisms.
The 96-hour NOEC for zebra fish (Danio rerio) was found to be 100 mg/L and the 96-hour LC50 was determined to be >100 mg/L.
The 48-hour NOEC for Daphnia magna was found to be 216 mg/L and the EC50 was determined to be 540 mg/L.
The 72-hour NOEC for Pseudokirchneriella subcapitata for growth rate was found to be 8.7 mg/L and the ErC50 was found to be 740 mg/L.
The 3 -hour EC50 and NOEC for activated sludge microorganisms were both >1000 mg/L.
In the chemical safety assessment performed according to Article 14(3) in connection with Annex I section 3 (Environmental Hazard Assessment) no hazard was identified. Therefore according to REACH Annex I (5.0) exposure estimation is not necessary. Consequently, in accordance with Column 2 of REACH Annex IX, long term studies do not formally need to be conducted as all identified uses of the substance are assessed as safe for the environment.
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