Registration Dossier
Registration Dossier
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EC number: 231-818-8 | CAS number: 7757-79-1
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Induction of cell death in the intestinal crypt of mice following oral administration of nitrate and nitrite.
- Author:
- Grudzinski, I.P. and Law, F.C.P.
- Year:
- 1 998
- Bibliographic source:
- Bull. Environ. Contam. Toxicol. 60:185-193
Materials and methods
- Type of study / information:
- Potassium nitrate solution was administered by oral intubation in acute doses (50, 100, 200, or 400 mg/kg body weight). Groups of 4 or more animals were killed by cervical dislocation at various post-dosing periods (1, 2, 3, 4, 5, 6, 8, 10, and 12 hours).
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- no
Test material
- Reference substance name:
- Potassium nitrate
- EC Number:
- 231-818-8
- EC Name:
- Potassium nitrate
- Cas Number:
- 7757-79-1
- Molecular formula:
- HNO3.K
- IUPAC Name:
- potassium nitrate
- Test material form:
- solid: crystalline
- Details on test material:
- Name of test material: potassium nitrate (KNO3)
Physical appearance: colourless crystalline solid or a white crystalline or granular powder
Constituent 1
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
