Fatty acids, C8-10

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.02 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.15 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.002 mg/L

Assessment factor:

100

Extrapolation method:

assessment factor

PNEC marine water (intermittent releases):

0.015 mg/L

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

912 mg/L

Assessment factor:

1

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

0.295 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

0.029 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

0.047 mg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Additional information

Toxicity studies on aquatic organisms are available for the different members of the Fatty Acids category. For the substance fatty acids, C8-10, no toxictiy studies are available. Thus, read-across is performed to studies conducted to the individual constituents (> 10%) of the UVCB substance: octanoic (C8, CAS 124-07-2) and decanoic acid (C10, CAS 334-48-5). Thus PNEC (freshwater and marine) calculations are based on the EC50/NOEC values available for these two constituents. The toxicity data for octanoic acid and decanoic acid show an increasing acute as well as chronic toxicity to aquatic organisms with increasing chain length. PNECsediment and PNECsoil are based on the equilibrium partitioning calculation method with the freshwater and marine PNEC values. Due to the low potential for bioaccumulation, the PNECoral is not determined.

Conclusion on classification

Classification related key information (based on current available data)

Degradation:

-         Biodegradation: readily biodegradable: 62 – 105 % after 30 d (O2 consumption, OECD 301 D); RA CAS 124-07-2, CAS 143-07-7

Bioaccumulation:

-  Log Pow = 3.1 (OECD 107)

- BCF = 225 L/kg after 28 days (OECD 305 E); RA CAS 629-25-4

- BCF of C8 - C10: 83.64 - 378.7 L/kg (EPISuite, BCFBAF, Arnot-Gobas model)

 Aquatic acute toxicity:

-         Fish: LC50 (96 h) = 18.9 mg/L (nominal, Lepomis macrochirus); RA CAS 334-48-5

-         Aquatic invertebrates: EC50 (48 h) > 21 mg/L (meas. geom. mean, mobility of Daphnia magna, OECD 202); RA CAS 334 -48-5

-         Algae: ErC50 (72 h) = 15 mg/L (nominal, growth rate, OECD 201); RA CAS 334-48-5

 Aquatic chronic toxicity:

-         Fish: NOEC (28 d) = 6.4 mg/L (nominal, growth rate of Danio rerio, OECD 305 E); RA CAS 629-25-4

-         Aquatic invertebrates: NOEC (21 d) = 0.2 mg/L (nominal, reproduction rate of Daphnia magna, OECD 211); RA CAS 334 -48 -5

-         Algae: NOErC (72 h) = 3.2 mg/L (nominal, growth rate, OECD 201); RA CAS 334 -48 -5

Conclusion on classification

Acute and chronic toxicity data are available for all three trophic levels. The lowest effect value derived from short term toxicity studies (E(L)C50) was greater than 1 mg/L. Thus, according to the 7th ATP of Regulation (EC) No 1272/2008 (CLP), the tested substance does not need to be classified as acutely toxic to the environment. Furthermore, the tested substance is rapidly degradable while long term studies with organisms of the three trophic levels resulted in the lowest NOEC (21 d) of 0.2 mg/L (nominal) identified for aquatic invertebrates. Thus, the substance needs to be classified as “chronic category 3” (H412) according to the 7th ATP of Regulation (EC) No 1272/2008 (CLP).