Registration Dossier
Registration Dossier
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EC number: 202-429-0 | CAS number: 95-53-4
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- other: review
- Adequacy of study:
- supporting study
- Reliability:
- other: peer-reviewed publication
- Rationale for reliability incl. deficiencies:
- other: peer reviewed publication
Data source
Reference
- Reference Type:
- publication
- Title:
- o-TOLUIDINE CAS No: 95-53-4 SIDS Initial Assessment Report.
- Author:
- CICAD 1998 cited in OECD SIDS
- Year:
- 2 006
- Bibliographic source:
- UNEP Publications
Materials and methods
- Type of study / information:
- citation of a review
- Endpoint addressed:
- basic toxicokinetics
Test material
- Reference substance name:
- o-toluidine
- EC Number:
- 202-429-0
- EC Name:
- o-toluidine
- Cas Number:
- 95-53-4
- Molecular formula:
- C7H9N
- IUPAC Name:
- 2-methylaniline
- Test material form:
- other: liquid
Constituent 1
Results and discussion
- Results:
- Biological monitoring to assess human exposure to o-toluidine indicates that absorption may occur through inhalation and dermal contact;
however,quantitative information was not identified. o-toluidine bindes to hemoglobin. N-acetylated metabolites of o-toluidine are eliminated
in the urine.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
