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EC number: 232-164-6 | CAS number: 7789-41-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1978
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 978
- Report date:
- 1978
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- no guideline available
- GLP compliance:
- no
- Test type:
- other: Acute Inhalation Toxicity study in Rats
- Limit test:
- no
Test material
- Reference substance name:
- Calcium bromide
- EC Number:
- 232-164-6
- EC Name:
- Calcium bromide
- Cas Number:
- 7789-41-5
- Molecular formula:
- CaBr2
- IUPAC Name:
- calcium bromide
- Details on test material:
- Calcium Bromide solid, white (fine) powder
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: Charles River CD
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- Five male and 5 female Charles River CD rats were used in the study of the compound. The male rats weighed from 210 to 226 grams, and the females from 200 to 210 grams. The rats were housed individually in wire-mesh cages and were kept throughout the pre-and postexposure periods in a temperature and humidity controlled room i n accordance with standards outlined in the "Guide For the Care and Use of Laboratory Animals; DHEW No. (N.I.H . 74-23) 1974". Purina Laboratory Chow and water were supplied ad libitum except when the rats were in the exposure chamber.
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- whole body
- Vehicle:
- not specified
- Details on inhalation exposure:
- During exposure, the rats were caged individually in compartmented wire-mesh exposure cages. The cages were placed i n a 160- liter cubical stainless steel and glass chamber. A constant chamber airflow was maintained by means of a rotary centrifugal air pump located at the exhaust side of the chamber. The chamber exhaust was filtered with an activated charcoal filter and a Cambridge Absolute filter before being discharged outside of the laboratory.
- Analytical verification of test atmosphere concentrations:
- no
- Duration of exposure:
- ca. 1 h
- Concentrations:
- 204 mg/l
- No. of animals per sex per dose:
- 5
- Control animals:
- no
- Statistics:
- no further details
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- other: no effect
- Effect level:
- ca. 204 mg/L air (nominal)
- Based on:
- test mat.
- Remarks on result:
- other: no effect observed
- Mortality:
- There was no death occuring among the rats.
- Clinical signs:
- other: The immediate response of the rats to the experimental atmosphere was an increase of activity in preening. After 10 minutes of exposure, the rats began to settle down. There was no sign of toxicity observed during the 1-hour exposure. At the termination o
- Body weight:
- The body weight gain of the rats appeared to be normal throughout the 14-day observation period. All rats gained weight. The initial and final mean body weights were 212 +- 1 0 and 269 +- 36 grams, respectively.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information
- Conclusions:
- Inhalation exposure of rats for 1 hour to a dust atmosphere of Calcium Bromide at calculated concentration of 204 mg/l did not result in any observable toxic effects during or after the exposure.
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