Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 220-667-3 | CAS number: 2855-19-8
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The determinations were done according to OECD Guideline for the Testing of Chemicals 111.
Calculation of values for T = 20 °C/25 °C
Assuming first order reactions, hydrolysis rates and half-lives for other temperatures can be calculated at pH 4, pH 7 and pH 9 according to the Arrhenius equation.
By plotting the natural logarithm of the rate constants against the reciprocal of the temperature (K), the rate constants and half-lives at 20 °C and 25 °C were obtained by extrapolation.
Half-lives at 20 °C and 25 °C, calculated from the measured values:
pH value T emperature t½ [h]
pH 4 20 °C 117.9
pH 4 25 °C 77.1
pH 7 20 °C 183.2
pH 7 25 °C 142.2
pH 9 20 °C 187.9
pH 9 25 °C 157.9
The content of the hydrolsis product 1,2-dodecanediol in the combined extracts was determined to be: 4.8 mg/L
Key value for chemical safety assessment
Additional information
In Annex VIII column 2 of the Regulation (EC) No 1907/2006 REACH concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), it is suggested, that a study on the "Hydrolysis as function of pH" does not need to be conducted if the " substance is is readily biodegradable". Since the substance is readily biodegradable (with failing the 10d window), no test for hydrolysis is performed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
