Registration Dossier
Registration Dossier
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EC number: 274-395-5 | CAS number: 70209-97-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 06 July 1975
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: In-house SOP (method A.11) validated by Ciba which is comparable to standard guideline.
- Deviations:
- not specified
- Principles of method if other than guideline:
- In-house SOP (method A.11) validated by Ciba which is comparable to standard guideline.
- GLP compliance:
- no
- Test organisms (species):
- Oncorhynchus sp.
- Details on test organisms:
- Trout fish- 8 per concentraion
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Test temperature:
- 13 °C
- pH:
- 7.7 - 7.9
- Nominal and measured concentrations:
- 100, 200, 1000 mg/l
- Duration:
- 48 h
- Dose descriptor:
- other: TL50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- other: TL100
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Validity criteria fulfilled:
- yes
- Conclusions:
- The TL50 of FAT 20075/A in Rainbow trout fishes was determined to be >1000 mg/L.
- Executive summary:
An acute fish toxicity test was performed according to in house SOP (method A.11) validated by Ciba which is comparable to standard guideline i.e. OECD TG 203. Rainbow trout were used in this test. All the fish exposed to all three concentration were survived at 24 and 48 h observations. No mortality was observed till 1000 mg/l concentration for the duration of the test. Hence, based on the study results, TL50of FAT 20075/A was determined to be 1000 mg/L.
Reference
Description of key information
An acute fish toxicity test was performed according to in house SOP (method A.11) validated by Ciba which is comparable to standard guideline i.e. OECD TG 203. Rainbow trout were used in this test. All the fish exposed to all three concentration were survived at 24 and 48 h observations. No mortality was observed till 1000 mg/l concentration for the duration of the test. Hence, based on the study results, TL50 of FAT 20075/A was determined to be 1000 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1 000 mg/L
Additional information
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