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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
22 October 1998 to 15 January 1999
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Water solubility:
255.6 g/L
Conc. based on:
act. ingr.
Temp.:
20 °C
pH:
5.5
Details on results:
Water solubility of the test substance at a temperature of 20°C (corrected to the purily of 73 % (w/w)): 255.6 g/l (RSD:4.7%)

Peak areas of experiment A to C (dilution factor: 1:5000) and applied standard

Experiment/Stirring Time at 30⁰C (h)

Standard concentration (mg/l)

Peak area (mV*min)

Water solubility (g/l)

 

Mean value

Final mean value

A 24h

103.84

351.298

 

 

 

 

 

243.313

359.60

368.28

 

 

 

255.051

376.95

 

365.28

 

114.94

395.280

 

 

 

 

 

243.313

353.75

362.29

 

 

 

255.051

370.82

 

 

B 48h

114.94

395.280

 

 

 

 

 

237.941

345.94

344.64

 

 

 

236.149

343.34

 

352.31

 

117.54

386.990

 

 

 

 

 

237.941

361.35

359.99

 

 

 

236.149

358.63

 

 

C 72h

117.54

386.990

 

 

 

 

 

209.840

318.67

325.34

 

 

 

218.617

332.00

 

332.88

 

110.54

347.818

 

 

 

 

 

209.840

333.45

340.42

 

 

 

218.617

347.39

 

 

 

Conclusions:
Water solubility of the test substance at a temperature of 20°C is 255.6 g/L based on the active ingredient.
Executive summary:

The water solubility of the test substance at a temperature of 20°C has been determined in accordance with the "flask method" described in guideline 92/69/EEC, appendix, A.6. in compliance with GLP.

 

It was found to be 255.6 g/L (RSD:4.7%)

 

Description of key information

The water solubility of the test substance at a temperature of 20°C has been determined in accordance with the "flask method". It was found to be 255.6 g/L (RSD: 4.7%)

Key value for chemical safety assessment

Water solubility:
255.6 g/L
at the temperature of:
20 °C

Additional information

The water solubility of the test substance at a temperature of 20°C has been determined in accordance with the "flask method" described in guideline 92/69/EEC, appendix, A.6. in compliance with GLP.

 

It was found to be 255.6 g/L (RSD:4.7%)