Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Comparable to guideline study with acceptable restrictions.

Data source

Reference
Reference Type:
other: inquiry data
Title:
Unnamed
Year:
2014

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Annex V, B.4.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
A mixture of: thiobis(4,1-phenylene)-S,S,S',S'-tetraphenyldisulfonium bishexafluorophosphate; diphenyl(4-phenylthiophenyl)sulfonium hexafluorophosphate
EC Number:
404-986-7
EC Name:
A mixture of: thiobis(4,1-phenylene)-S,S,S',S'-tetraphenyldisulfonium bishexafluorophosphate; diphenyl(4-phenylthiophenyl)sulfonium hexafluorophosphate
Cas Number:
74227-35-3
IUPAC Name:
(4-{[4-(diphenylsulfaniumyl)phenyl]sulfanyl}phenyl)diphenylsulfanium; diphenyl[4-(phenylsulfanyl)phenyl]sulfanium; tris(hexafluoro-λ⁵-phosphanuide)

Test animals

Species:
other: White Russian Rabbit

Test system

Type of coverage:
occlusive
Vehicle:
water
Amount / concentration applied:
0.5 g test substance moistened with 0.38 ml watar
Duration of treatment / exposure:
4 hours
Number of animals:
2 males, 1 female

Results and discussion

Any other information on results incl. tables

INTENSITY AND DURATION OF EFFECTS (REFERRING TO THE DOSE GROUPS)

A very slight erythema could be observed in 1 animal for 2 days.

Applicant's summary and conclusion