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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
1-Chlor-2-methyl-3-nitrobenzol (2-Chlor-6-nitrotoluol) BUA Stoffbericht 61
Author:
Beratergremium für umweltrelevante Altstoffe (BUA)
Year:
1991
Bibliographic source:
VCH Verlagsgesellschaft mbH, Weinheim, ISBN 3-527-28427-3
Reference Type:
study report
Title:
Unnamed
Year:
1984

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
GLP compliance:
yes
Test type:
acute toxic class method

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chloro-6-nitrotoluene
EC Number:
201-475-9
EC Name:
2-chloro-6-nitrotoluene
Cas Number:
83-42-1
Molecular formula:
C7H6ClNO2
IUPAC Name:
1-chloro-2-methyl-3-nitrobenzene

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage

Results and discussion

Effect levelsopen allclose all
Sex:
female
Dose descriptor:
LD50
Effect level:
2 320 mg/kg bw
Sex:
male
Dose descriptor:
LD50
Effect level:
2 560 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU