Registration Dossier
Registration Dossier
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EC number: 201-810-9 | CAS number: 88-21-1
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Available data for 4- aminobenzene sulfonic acid, which has been used as a read-across chemical to the target chemical 2-aminobenzenesulphonic acid, indicates low bio-accumulation potential for the read-across chemical. Thus, is can be assumed that the target chemical by virtue of having similar functional groups as the read-across shall also exhibit low bio-accumulation potential.
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
Additional information
4-Aminobenzene sulfonic acid can be absorbed from the gastrointestinal tract. Absorption through the lungs appears to be possible; absorption of an intratracheally-instilled solution of 4- aminobenzene sulfonic acid has been detected in the rat. Accumulation does not take place in mammals; excretion after oral administration mainly occurs within 24 hr. 4-Aminobenzene sulfonic acid is excreted either unchanged or as the N-acetyl metabolite, in the urine and the feces in rats.
Thus, is can be assumed that the target chemical by virtue of having similar functional groups as the read-across shall also exhibit low bio-accumula tion potential.
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