Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 619-635-5 | CAS number: 12567-73-6
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Key study: experimental results from a study report, according to OECD guideline 471 and directive 2000/32/EC, part B.13/14. Salmonella typhimurium TA97a, TA98, TA100, TA102 and TA1535, with and without metabolic activation. The
test was performed according to the "direct plate incorporation method". Negative and positive controls were included.In none of the concentrations tested and with none of the strains used an increase of the mutation frequency to more than the threshold values was obtained. Metabolic activation did not change these results.
It is concluded that Zirkonium-tetrakis(isobutyrato) is non-mutagenic in the Ames test with the strains TA97a, TA98, TA100, TA102 and TA1535 with and without an external metabolising system up to the limit of toxicity.
Short description of key information:
Genetic toxicity: key study: results from a study report leadinf to the conclusion that Zirkonium-tetrakis(isobutyrato) is non-mutagenic in the Ames test with the strains TA97a, TA98, TA100, TA102 and TA1535 with and without an external metabolising system up to the limit of toxicity.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
