Registration Dossier
Registration Dossier
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EC number: 207-050-4 | CAS number: 428-59-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The scientific validity of the (Q)SAR model has been established in accordance with the OECD Principles for (Q)SAR Model Validation. This study was selected as the key study because the information provided for the hazard endpoint is sufficient for the purpose of classification and labelling and/or risk assessment.
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
- Principles of method if other than guideline:
- ECOSAR V1.11
QMRF and QPRF are attached in IUCLID. - GLP compliance:
- not specified
Test material
- Reference substance name:
- Trifluoro(trifluoromethyl)oxirane
- EC Number:
- 207-050-4
- EC Name:
- Trifluoro(trifluoromethyl)oxirane
- Cas Number:
- 428-59-1
- Molecular formula:
- C3F6O
- IUPAC Name:
- 2,2,3-trifluoro-3-(trifluoromethyl)oxirane
Constituent 1
Test organisms
- Test organisms (species):
- other: green algae
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 73.8 mg/L
- Nominal / measured:
- estimated
- Remarks on result:
- other: predicted using the estimated KOWWIN LogKow of 1.72 (QPRF) and the measured average water solubility of 0.0163 mg/L
Any other information on results incl. tables
Supporting documentation are provided in the attached QPRF and QMRF.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- 96-hour LC50 (algae) >73.8 mg/L
This study and the conclusions which are drawn from it fulfil the quality criteria (validity, reliability, repeatability). - Executive summary:
The 96-hour LC50 to algae was predicted to be >73.8 mg/L.
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