Registration Dossier
Registration Dossier
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EC number: 201-924-9 | CAS number: 89-62-3
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Database
- Title:
- 2-Nitro-4-metyhylaniline
- Author:
- KEMI Swedish Chemical Agency
- Year:
- 2 011
- Bibliographic source:
- Kemi-Riskline database; Toxikologische Bewertung. Heidelberg, Berufsgenossenschaft der chemischen Industrie Vol:118 (2000) 18 p
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Kemi-Riskline database
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-nitro-p-toluidine
- EC Number:
- 201-924-9
- EC Name:
- 2-nitro-p-toluidine
- Cas Number:
- 89-62-3
- Molecular formula:
- C7H8N2O2
- IUPAC Name:
- 4-methyl-2-nitroaniline
- Details on test material:
- - Name of test material: 2-nitro-p-toluidine
- Molecular formula: C7H8N2O2
- Molecular weight: 152.15
- Substance type: organic
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Reversibility:
- no data
- Remarks on result:
- other: no primary irritant effect
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- 2-nitro-p-toluidine is found to be non-irritating to skin of the rabbit.
- Executive summary:
2-nitro-p-toluidine is found to be non-irritating to skin of the rabbit.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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