Registration Dossier
Registration Dossier
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EC number: 215-183-4 | CAS number: 1310-65-2
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin corrosion: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2009
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- other:
- Title:
- ECHA disseminated Dossier of Lithium hydroxide (CAS 1310-65-2)
- Year:
- 2 022
- Bibliographic source:
- ECHA disseminated Dossier of Lithium hydroxide (CAS 1310-65-2), query date 2022-03-09
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 435 (In Vitro Membrane Barrier Test Method for Skin Corrosion)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Lithium hydroxide
- EC Number:
- 215-183-4
- EC Name:
- Lithium hydroxide
- Cas Number:
- 1310-65-2
- Molecular formula:
- HLiO
- IUPAC Name:
- lithium hydroxide
Constituent 1
In vitro test system
- Test system:
- other: Corrositex® test kit
Results and discussion
In vitro
Resultsopen allclose all
- Irritation / corrosion parameter:
- penetration time (in minutes)
- Run / experiment:
- A
- Value:
- 24.42
- Vehicle controls validity:
- valid
- Negative controls validity:
- not examined
- Positive controls validity:
- valid
- Remarks on result:
- other: mean of 4 replicates 24 min 25 sec (=24.42)
- Irritation / corrosion parameter:
- penetration time (in minutes)
- Run / experiment:
- B
- Value:
- 21
- Vehicle controls validity:
- valid
- Negative controls validity:
- not examined
- Positive controls validity:
- valid
- Remarks on result:
- other: mean of 4 replicates 20 min 59 sec (=21)
Applicant's summary and conclusion
- Interpretation of results:
- Category 1B (corrosive) based on GHS criteria
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