Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 251-607-4 | CAS number: 33629-47-9
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 4-(tert-butyl)-N-sec-butyl-2,6-dinitroaniline
- EC Number:
- 251-607-4
- EC Name:
- 4-(tert-butyl)-N-sec-butyl-2,6-dinitroaniline
- Cas Number:
- 33629-47-9
- Molecular formula:
- C14H21N3O4
- IUPAC Name:
- N-sec-butyl-4-tert-butyl-2,6-dinitroaniline
- Reference substance name:
- Xylene
- EC Number:
- 215-535-7
- EC Name:
- Xylene
- Cas Number:
- 1330-20-7
- Molecular formula:
- C8H10
- IUPAC Name:
- m-xylene
Constituent 1
impurity 1
Study design
- Details on test conditions:
- Sterile aqueous 14C-Butralin test solutions at pH 4. 7 and 9 were kept in the dark at 25°C for up to 6 months.
Duration of testopen allclose all
- Duration:
- 6 mo
- pH:
- 4
- Temp.:
- 25 °C
- Initial conc. measured:
- ca. 0.15 mg/L
- Duration:
- 6 mo
- pH:
- 9
- Temp.:
- 25 °C
- Initial conc. measured:
- ca. 0.15 mg/L
- Number of replicates:
- 14
Results and discussion
- Preliminary study:
- During the 5-day preliminary test no degradation occurred at 50°C, therefore the compound is considered hydrolytically stable with a alf-life of greater than one year (OECD, 1981)
- Transformation products:
- no
Total recovery of test substance (in %)open allclose all
- % Recovery:
- ca. 101
- St. dev.:
- 6.1
- pH:
- 9
- Temp.:
- 25 °C
- Duration:
- ca. 6 mo
- % Recovery:
- ca. 99.8
- St. dev.:
- 2.6
- pH:
- 7
- Temp.:
- 25 °C
- Duration:
- ca. 6 mo
- % Recovery:
- ca. 97.5
- St. dev.:
- 4.9
- pH:
- 4
- Temp.:
- 25 °C
- Duration:
- ca. 6 mo
Dissipation DT50 of parent compound
- Key result
- Remarks on result:
- hydrolytically stable based on preliminary test
- Remarks:
- Due to very little degradation after incubation for six months at pH 4, 7 and 9 no half-life canbe calculated.
Applicant's summary and conclusion
- Conclusions:
- 14C-Butralin is considered hydrolytically stable.
- Executive summary:
After a six-month period at 25°C in the dark, less than 10% hydrolysis was observed at each pH tested. Of the initial concentrations, mean percentages of 101%, 91.8% and 94.2% parent compound remained at pH 4, 7 and 9, respectively. 14C-Butralin is considered hydrolytically stable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
