4-ethoxy-2,3-difluoro-4'-propyl-1,1'-biphenyl

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Feb 04 - Mar 15, 2011

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))

Deviations:

no

GLP compliance:

yes

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge, non-adapted

Details on inoculum:

no data

Duration of test (contact time):

28 d

Initial conc.:

30 mg/L

Based on:

test mat.

Parameter followed for biodegradation estimation:

O2 consumption

Details on study design:

No details available

Reference substance:

aniline

Test performance:

The degradation of the control material (anline) demonstrated suitability of the test performed.

Key result

Parameter:

% degradation (O2 consumption)

Value:

0

Sampling time:

28 d

Remarks on result:

other: not readily biodegradable

Results with reference substance:

For the control material (anline) a degradation of 58, 70, 74 and 76 % was observed after 7, 14, 21, and 28 days.

BOD Data

	BOD / [mg]
	Day 7	Day 14	Day 21	Day 28
Blank (30 mg/L test material in deionised water)	0.0	0.0	0.0	0.0
Test 1 (100 mg/L sludge + 30 mg/L test material in basal culture medium)	1.7	3.4	5.9	7.0
Test 2 (100 mg/L sludge + 30 mg/L test material in basal culture medium)	1.7	3.4	5.9	6.7
Test 3 (100 mg/L sludge + 30 mg/L test material in basal culture medium)	1.9	3.8	5.9	7.0
Control (100 mg/L sludge + 100 mg/L aniline in basal culture medium)	54.4	68.5	74.5	76.3
Control (100 mg/L sludge in basal culture medium)	1.9	5.2	7.1	7.5

Validity criteria fulfilled:

yes

Interpretation of results:

not readily biodegradable

Conclusions:

The test material is not readily biodegradable in this screening test system.

Executive summary:

The study was performed to obtain information about the degradation behavior of the test material in aqueous environment. This study was performed according to GLP and the methods applied are fully compliant with OECD 301C.
Under the test conditions the biodegradation of the test material reached 0 % after 28 days of incubation. The percentage biodegradation did not exceed 60 % within the 10-day window and after 28 days of incubation.
For the control material (anline) a degradation of 58, 70, 74 and 76 % was observed after 7, 14, 21, and 28 days of incubation, thus confirming the suitability of the used activated sludge inoculum.
The oxygen demand in the abiotic control was zero.

The test material is not readily biodegradable in this screening test system.

Description of key information

This study was performed according to GLP and the methods applied are fully compliant with OECD 301C. The test material is not readily biodegradable in this screening test system.

Key value for chemical safety assessment

Biodegradation in water:

under test conditions no biodegradation observed

Type of water:

freshwater

Additional information

The study was performed to obtain information about the degradation behavior of the test material in aqueous environment. This study was performed according to GLP and the methods applied are fully compliant with OECD 301C.
Under the test conditions the biodegradation of the test material reached 0 % after 28 days of incubation. The percentage biodegradation did not exceed 60 % within the 10-day window and after 28 days of incubation.
For the control material (anline) a degradation of 58, 70, 74 and 76 % was observed after 7, 14, 21, and 28 days of incubation, thus confirming the suitability of the used activated sludge inoculum.
The oxygen demand in the abiotic control was zero.

The test material is not readily biodegradable in this screening test system.