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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian somatic and germ cell study: gene mutation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
review article or handbook
Title:
CAS 108-73-6 OECD Toolbox v3.4.0 experimental data for an Ames test and for in vitro chromosome aberration in Chinese hamster lung cells, and for a micronucleus test
Author:
Japan Ministry of Health, Labour and Wellfare
Year:
2018
Bibliographic source:
OECD Toolbox v3.4.0
Report date:
2018

Materials and methods

Test guideline
Guideline:
OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)
GLP compliance:
not specified
Remarks:
the actual study was performed before 2008
Type of assay:
mammalian erythrocyte micronucleus test

Test material

Constituent 1
Chemical structure
Reference substance name:
Phloroglucinol
EC Number:
203-611-2
EC Name:
Phloroglucinol
Cas Number:
108-73-6
Molecular formula:
C6H6O3
IUPAC Name:
benzene-1,3,5-triol

Test animals

Species:
mouse
Strain:
CD-1

Administration / exposure

Route of administration:
not specified

Results and discussion

Test results
Key result
Sex:
male
Genotoxicity:
negative
Toxicity:
not specified

Applicant's summary and conclusion