Registration Dossier
Registration Dossier
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EC number: 222-908-8 | CAS number: 3658-77-3
Endpoint summary
Administrative data
Description of key information
Two experimental studies (based on international guidelines and GLP compliance) and one QSAR result (iSafeRat® Holistic HA-QSAR v1.8) are available to assess the aquatic toxicity of the registered substance, on aquatic invertebrates and algae.
The experimental short-term toxicity study on the aquatic invertebrate, Daphnia magna, was performed on the registered substance. In this study, the 48h-EC50 value, based on analytically confirmed nominal concentration (by TOC analysis), was determined at 6.8 mg/L.
On algae, the experimental study was performed on the registered substance in order to evaluate its toxicity towards the freshwater green alga Desmodesmus subspicatus. In this study, the 72h-ErC50 and 72h-ErC10 values were determined at 194.03 and 7.20 mg/L, respectively, for growth rate, based on the geometric mean measured concentrations. This experimental ErC50 value was supported by a QSAR prediction using iSafeRat® holistic HA-QSAR v1.8 model. The predicted 72h-ErC50 value was determined at 123 mg/L.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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