Registration Dossier
Registration Dossier
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EC number: 222-908-8 | CAS number: 3658-77-3
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Environmental fate and pathways:
The registered substance is readily biodegradable and therefore is not persistent in the environment. In addition, with a log Kow value at 0.95, the registered substance has not a potential for bioaccumulation according to the Regulation (EC) No.1272/2008 (CLP) criteria (log Kow < 4.0) and PBT criteria (log Kow < 4.5).
Aquatic toxicity:
Two experimental studies (based on international guidelines and GLP compliance) and one QSAR result(iSafeRat® Holistic HA-QSAR v1.8) are available to assess the aquatic toxicity of the registered substance, on aquatic invertebrates and algae.
The experimental short-term toxicity study on the aquatic invertebrate, Daphnia magna, was performed on the registered substance. In this study, the 48h-EC50 value, based on analytically confirmed nominal concentration (by TOC analysis), was determined at 6.8 mg/L.
On algae, the experimentalstudy was performed on the registered substance in order to evaluate its toxicity towards the freshwater green alga Desmodesmus subspicatus. In this study, the 72h-ErC50 and 72h-ErC10 values were determined at 194.03 and 7.20 mg/L, respectively, for growth rate, based on the geometric mean measured concentrations. This experimental ErC50 value was supported by a QSAR prediction usingiSafeRat® holistic HA-QSAR v1.8 model. The predicted 72h-ErC50 value was determined at 123 mg/L.
Conclusion on classification
No harmonised classification is available.
1 < lowest EC50 value < 10 mg/L; readily biodegradable; log Kow < 4.0.
Classification according to the Annex VI of the Regulation (EC) No 1272/2008 (CLP): The registered substance is not classified for the environment.
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