Registration Dossier
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EC number: 944-045-2 | CAS number: -
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- August 4, 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Principles of method if other than guideline:
- Laser light scattering. The test was performed according to the SOP - STR 071 (Hydro 2000S) protocol.
Particle size distribution was analysed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measure particle size. It measures intensity of light scattered as a laser beam passes through a dispersed particulate sample. The scattering pattern is then analysed to calculate particle size. - GLP compliance:
- no
- Type of method:
- Laser scattering/diffraction
- Type of distribution:
- volumetric distribution
- Mass median aerodynamic diameter:
- ca. 28.004 µm
- Remarks on result:
- other: after 2 minutes sonication
- Percentile:
- D50
- Mean:
- ca. 28.004 µm
- Remarks on result:
- other: after 2 minutes of ultrasonic treatment
- Percentile:
- D10
- Mean:
- ca. 2.57 µm
- Remarks on result:
- other: after 2 minutes of ultrasonic treatment
- Percentile:
- D90
- Mean:
- >= 91.374 µm
- Remarks on result:
- other: after 2 minutes of ultrasonic treatment
- Conclusions:
- d(0.1): 2.570 µm
d(0.5): 28.004 µm
d(0.9): 91.374 µm - Executive summary:
Method
Particle size distribution was analysed using Mastersizer 2000 tool, which uses laser diffraction to measure particle size. This is obtained by measuring the intensity of light scattered as a laser beam passes through a dispersed particulate sample. The scattering pattern is then analysed to calculate particle size.
Result
Analysis carried out after 2 minutes of ultrasonic treatment:
d(0.1): 2.570 µm
d(0.5): 28.004 µm
d(0.9): 91 .374 µm.
Reference
Description of key information
MMD = 28.004 µm.
Additional information
Laser diffraction analysis.
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