Registration Dossier
Registration Dossier
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EC number: 266-037-1 | CAS number: 65997-01-5
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 431
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- 65997-01-5 TOS E
- IUPAC Name:
- 65997-01-5 TOS E
- Reference substance name:
- 65997-01-5 TOS 24
- IUPAC Name:
- 65997-01-5 TOS 24
- Reference substance name:
- 65997-01-5 TOS 23
- IUPAC Name:
- 65997-01-5 TOS 23
Constituent 1
Constituent 2
Constituent 3
Results and discussion
Any other information on results incl. tables
The relative mean viability of the test item treated tissues was 98.8% after the 3 minute exposure period and 104.2% after the 60 minute exposure period. (TOS 24)
The relative mean viability of the test item treated tissues was 94.8% after the 3 minute exposure period and 94.7% after the 60 minute exposure period. (TOS 24)
The relative mean viability of the test item treated tissues was 101.9 % after the 3 minute exposure period and 55.9 % after the 60 minute exposure period. (TOS E)
In conclusion all three test items were not considered to have the potential to be corrosive in vivo.
Applicant's summary and conclusion
- Conclusions:
- None of the samples were considered to be corrosive under the conditions of the study.
- Executive summary:
In a well conducted EpiDerm study to evaluate the corrosivity of three test items, the results were as follows,
The relative mean viability of the test item treated tissues was 98.8% after the 3 minute exposure period and 104.2% after the 60 minute exposure period. (TOS 24)
The relative mean viability of the test item treated tissues was 94.8% after the 3 minute exposure period and 94.7% after the 60 minute exposure period. (TOS 24)
The relative mean viability of the test item treated tissues was 101.9 % after the 3 minute exposure period and 55.9 % after the 60 minute exposure period. (TOS E)
In conclusion all three test items were not considered to have the potential to be corrosive in vivo.
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