Registration Dossier
Registration Dossier
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EC number: 203-561-1 | CAS number: 108-21-4
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Isopropyl acetate is considered readily biodegradable in freshwater under aerobic conditions.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Studies have been conducted to assess the biodegradation of isopropyl acetate. A 20-day biological oxygen demand (BOD) test reported 61% biodegradation by 5 days, 72% by 10 days, 74% by day 15, and 76% by day 20, using unacclimated domestic sewage. Measured COD (chemical oxygen demand) was reported as 2.04 mg/mg. (Price, et al., 1974). Since the biodegradation rate in the primary study exceeds the needed 60% and the 10-day time window, isopropyl acetate can be considered “readily biodegradable” under aerobic conditions. Studies using adapted innoculum showed no increase in degradation rates. Studies using non-adapted raw sewage and synthetic seawater (Price, et al., 1974), reported 62% and 49% degradation after 20 days, respectively, although it was noted that one of the readily biodegradable reference controls showed only limited degradation in this study.
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