Registration Dossier
Registration Dossier
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EC number: 224-338-5 | CAS number: 4316-73-8
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable screening method
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 967
- Report date:
- 1967
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 403 (Acute Inhalation Toxicity)
- Version / remarks:
- Inhalation hazard test as in the annex of the guideline
- GLP compliance:
- no
- Test type:
- standard acute method
Test material
- Reference substance name:
- Sodium sarcosinate
- EC Number:
- 224-338-5
- EC Name:
- Sodium sarcosinate
- Cas Number:
- 4316-73-8
- Molecular formula:
- C3H7NO2.Na
- IUPAC Name:
- sodium (methylamino)acetate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- male/female
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- whole body
- Vehicle:
- other: water
- Analytical verification of test atmosphere concentrations:
- no
- Duration of exposure:
- 8 h
- Concentrations:
- nominal concentration: 3.41 mg/l
- No. of animals per sex per dose:
- 6 (tests were performed in 2 trials with 3 animals/sex/trial)
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: 8 days
- Necropsy of survivors performed: yes
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC0
- Effect level:
- 3.41 mg/L air (nominal)
- Exp. duration:
- 8 h
- Remarks on result:
- other: No mortalities observed
- Mortality:
- No mortalities observed
- Clinical signs:
- other: No abnormalities observed
- Body weight:
- not determined
- Gross pathology:
- One animal suffered from bronchitis
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
