2-nitro-4-(trifluoromethyl)benzonitrile

Guidance on Safe Use

First-aid measures

General advice:

Move out of dangerous area. Place and transport victim in stable position (lying sideways). Remove contaminated clothing immediately and dispose of safely.

 

Inhalation:

Move the victim to fresh air and keep at rest. Call a physician or poison control center immediately.

 

Skin contact:

Wash off thoroughly with plenty of soap and water, if available with polyethyleneglycol 400, subsequently rinse with water. Call a physician or poison control center immediately. 

 

Eye contact:

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a physician or poison control center immediately.

 

Ingestion

Keep at rest. Rinse mouth. Induce vomiting only, if: 1. patient is fully conscious, 2. medical aid is not readily available, 3. a significant amount (more than a mouthful) has been ingested and 4. time since ingestion is less than 1 hour. (Vomit should not get into the respiratory tract.) Call a physician or poison control center immediately.

 

Symptoms

Local: Sensitisation, Systemic: To date no symptoms are known.

Fire-fighting measures

Extinguishing media

Suitable: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Unsuitable: High volume water jet

 

Special hazards arising from the substance or mixture

In the event of fire the following may be released: Carbon monoxide, (CO), Nitrogen oxides (NOx), Hydrogen fluoride

Advice for firefighters: 

Special protective equipment for firefighters: In the event of fire and/or explosion do not breathe fumes. Wear selfcontained breathing apparatus and protective suit.

 

Further information:

Contain the spread of the fire-fighting media. Do not allow run-off from fire fighting to enter drains or water courses.

 

Accidental release measures

Person-related safety precautions:  

Avoid dust formation. Avoid contact with spilled product or contaminated surfaces. Use personal protective equipment. Remove all sources of ignition.

 

Measures for environmental protection:  

Do not allow to get into surface water, drains and ground water.

 

Methods and materials for containment and cleaning up

Measures for cleaning up: Use mechanical handling equipment. Clean contaminated floors and objects thoroughly, observing environmental regulations. Collect and
transfer the product into a properly labelled and tightly closed container.

Handling and storage

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.

 

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.

 

Precautions for safe handling

Advice on safe handling: Avoid dust formation. Use only in area provided with appropriate exhaust ventilation.

Advice on protection against fire and explosion

Dust may form explosive mixture in air. Keep away from heat and sources of ignition. Take measures to prevent the build up of electrostatic charge.

Hygiene measures:

Avoid contact with skin, eyes and clothing. Keep working clothes separately. Wash hands before breaks and immediately after handling the product. Remove contaminated clothing immediately and dispose of safely.

Conditions for safe storage, including any incompatibilities

Requirements for storage areas and containers: Keep containers tightly closed in a dry, cool and well-ventilated place. Store in original container. Store in a place accessible by authorized persons only. Keep away from direct sunlight.

Advice on common storage:

Keep away from food, drink and animal feedingstuffs.

 

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

3077

Shipping information

Proper shipping name and description:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.

Chemical name:

2-nitro-4-(trifluoromethyl)benzonitrile

Language:

English

Class or division:

Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances

Packing group:

Packing group III: Substances presenting low danger

Labels:

Packaging/Bulk: 9 +EHS
Haz ID 90, EAC 2Z

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

3077

Shipping information

Proper shipping name and description:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.

Chemical name:

2-nitro-4-(trifluoromethyl)benzonitrile

Language:

English

Class or division:

Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances

Packing group:

Packing group III: Substances presenting low danger

Labels:

Packaging/Bulk: 9 +EHS
Haz ID 90

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

3077

Shipping information

Proper shipping name and description:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.

Chemical name:

2-nitro-4-(trifluoromethyl)benzonitrile

Language:

English

Class or division:

Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances

Packing group:

Packing group III: Substances presenting low danger

EmS code:

F-A

S-F

Labels:

9

Marine pollutant

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

UN 3077

Shipping information

Proper shipping name and description:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.

Chemical name:

2-nitro-4-(trifluoromethyl)benzonitrile

Language:

English

Class or division:

Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances

Packing group:

Packing group III: Substances presenting low danger

Labels:

Packaging 9+EHS

Remarks

SpecialProvisions

Exposure controls / personal protection

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.

 

Exposure controls: 

Respiratory protection: Wear respirator with a particle filter mask (protection factor 10) conforming to European Norm EN149FFP2 or EN140P2 or equivalent.
Respiratory protection should only be used to control residual risk of short duration activities, when all reasonably practicable steps have been taken to reduce exposure at source e.g. containment and/or local extract ventilation. Always follow respirator manufacturer's instructions regarding wearing and maintenance.

 

Hand protection: Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion, and the contact time. Wash gloves when contaminated. Dispose of when contaminated inside, when perforated or when contamination on the outside cannot be removed. Wash hands frequently and always before eating, drinking, smoking or using the toilet.

Material	Nitrile rubber
Rate of permeability	> 480 min
Glove thickness	> 0,4 mm
Protective index	Class 6
Directive	Protective gloves complying with EN 374.

Eye protection: Wear goggles (conforming to EN166, Field of Use = 5 or equivalent) and faceshield (conforming to EN166, Field of Use = 3 or equivalent).

 

Skin and body protection: Wear standard coveralls and Category 3 Type 4 suit.

If there is a risk of significant exposure, consider a higher protective type suit.

Wear two layers of clothing wherever possible. Polyester/cotton or cotton overalls should be worn under chemical protection suit and should be professionally laundered frequently.

If chemical protection suit is splashed, sprayed or significantly contaminated, decontaminate as far as possible, then carefully remove and dispose of as advised by manufacturer.

General protective measures: If product is handled while not enclosed, and if contact may occur: Complete suit protecting against chemicals.

Stability and reactivity

Reactivity: Stable under normal conditions.

Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reactions: No hazardous reactions when stored and handled according to prescribed instructions.

Conditions to avoid: Extremes of temperature and direct sunlight.

Incompatible materials: Store only in the original container.

Hazardous decomposition products: No decomposition products expected under normal conditions of use.

Disposal considerations

During the whole life cycle of the substance all necessary measures in accordance to art. 18(4) of (EC) 1907/2006 are undertaken. The substance is handled under strictly controlled conditions.

Dispose in accordance with current regulations and, if necessary, after consultation with the site operator and/or with the responsible authority, the product may be taken to a waste disposal site or incineration plant.