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EC number: 222-619-7
CAS number: 3558-60-9
The dermal irritation potential of test
chemical (2- methoxy ethyl) benzene (CAS no.: 3558 -60 -9, E.C. no.: 222
-619 -7) was determined according to the OECD 439 test guideline for
this study. The MatTek EpiDerm™ model was used to assess the potential
dermal irritation of the test chemical by determining the viability of
the tissues following exposure to the test article via MTT. Tissues were
exposed to the test article and controls for ~one hour, followed by a 42
hour post-exposure recovery period. The viability of each tissue was
determined by MTT assay. The MTT data show the assay quality
controls were met and passed the acceptance of criteria. The Mean %
tissue viability compared to negative control (n=3) of the test chemical
was determined to be 2.3%.
Hence, under the current experimental test
conditions it was concluded that test chemical was considered to be
irritating to human skin and can thus be classified as ''Irritating to
skin in Category 2” as per CLP Regulation.
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