Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
basic toxicokinetics in vitro / ex vivo
Data waiving:
other justification
Justification for data waiving:
other:

Description of key information

Fast Pyrolysis Bio-oil (FPBO) is a complex mixture of a wide variety of molecules with different molecular mass derived from depolymerisation and fragmentation of cellulose, hemicellulose and lignin. Moreover, the composition is variable depending on starting materials of the process, and at the moment no full and detailed composition of FPBO is available (see section 1.2). The structure and physical and chemical properties of the identified components are highly variable.

Key value for chemical safety assessment

Additional information

None of the currently identified components of FPBO can be considered to be of so high toxicological or toxicokinetic significance that it would be suitable to be used as an indicator of toxicokinetics of FPBO. Also, none of the components is present at such a high proportion that it could be used as a representative of the mixture. All components are likely to have different toxicokinetic properties. Therefore, it is not possible to identify any component or a set of components that could be analysed for reliable evaluation of toxicokinetic properties of FPBO, and analysis of all innumerable components would not be technically feasible. Thus, there is currently no scientific or technical basis for analyzing toxicokinetics of FPBO. According to the currently available data no halogenated compounds are likely to be present at significant amounts. It is therefore unlikely that components of FPBO would show significant bioaccumulating potential.