Registration Dossier
Registration Dossier
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EC number: 233-786-0 | CAS number: 10361-29-2
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in mammalian cells
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The analogue Ammoniom carbamate shares the same functional group with Ammonium carbonte.
Data source
Reference
- Reference Type:
- other: read-across
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
- Principles of method if other than guideline:
- Read-across on analogue substance.
- GLP compliance:
- no
- Type of assay:
- mammalian cell gene mutation assay
Test material
- Reference substance name:
- Ammonium hydrogencarbonate
- EC Number:
- 213-911-5
- EC Name:
- Ammonium hydrogencarbonate
- Cas Number:
- 1066-33-7
- IUPAC Name:
- ammonium hydrogen carbonate
Constituent 1
Results and discussion
Any other information on results incl. tables
The analogue substance was negative in OECD 476 test.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative
Negative. - Executive summary:
The analogue substance was negative in OECD 476 test and ammonium cabronate is also considered to be negative.
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