3-bromopropene

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1979

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Study done with old guidelines but which are similar to actual. The study was conducted with a number of important groups of petroleum-derived chemicals. The conditions of the study can be judged acceptable.

Data source

Reference

Reference Type:

publication

Title:

Unnamed

Year:

1979

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: American Public Health Association - Static tank acute toxicity test

Deviations:

not specified

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

3-bromopropene

EC Number:

203-446-6

EC Name:

3-bromopropene

Cas Number:

106-95-6

Molecular formula:

C3H5Br

IUPAC Name:

3-bromoprop-1-ene

Constituent 2

Reference substance name:

1-bromoprop-2-ene

IUPAC Name:

1-bromoprop-2-ene

Details on test material:

No data

Sampling and analysis

Analytical monitoring:

not specified

Test organisms

Test organisms (species):

Carassius auratus

Details on test organisms:

Goldfish of uniform lenght (average 6.2 ± 0.7 cm) and weight (average 3.3 ± 1.0 g) and in good health

Study design

Test type:

static

Water media type:

freshwater

Total exposure duration:

24 h

Post exposure observation period:

None

Test conditions

Hardness:

Not reported
Local tap-water : alkali as Na+ = 30 mg/L

Test temperature:

20 ± 1°

pH:

Adjusted to 7.0 with NaOH or H2SO4.

Dissolved oxygen:

Due to volatility of allyl bromide the procedure had to be adapted slightly to avoid more than 10% loss. Test was done without aeration.
Test limited at 24 h to ensure that the dissolved oxygen content did not fall below 4.0 mg/L.

Salinity:

In mg/L: Cl- = 65 ; NO2- = 0 ; NO3- = 4 ; SO4 2- = 35 ; PO4 3- = 0.15 ; HCO3- = 25 ; SiO2 = 25 ; NH4+ = 0 ; Fe = 0.05 ; Mn = 0 ; Ca2+ = 100 ; Mg2+ = 8

Nominal and measured concentrations:

Not reported
The concentrations of the chemical in the solutions tested were determined before and efter each test, either with a total organic carbon analyser or by extraction and subsequent GC analysis.

Details on test conditions:

Test material was tested at a series of concentrations. In each test 6 fish were used. Solutions were contained in all-glass tanks measuring 42x 28x 28 cm.

Reference substance (positive control):

no

Results and discussion

Effect concentrations

Duration:

24 h

Dose descriptor:

LC50

Effect conc.:

800 µg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Applicant's summary and conclusion

Validity criteria fulfilled:

not specified

Conclusions:

LC50 of allyl bromide to Goldfish has been determined to be 800 µg/L.

Executive summary:

With the guidelines laid down by the American Public Health Association for static-tank acute toxicity test, LC50 of allyl bromide to Goldfish after 24 h test has been determined to be 800 µg/L.