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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
other information
Study period:
1995
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
EU Method C.1 (Acute Toxicity for Fish)
Version / remarks:
67/548/EEC (29.12.1992)
Deviations:
not specified
GLP compliance:
no
Analytical monitoring:
no
Details on sampling:
dead fishes were counted every 24 h over a period of 96 h.
Details on test solutions:
Stock solution: 10000 mg/l substance was stirred in dilution water for 24 h and was filtered afterwards
Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Test temperature:
21.6°C - 22.1°C
pH:
7.6 - 8.0
Dissolved oxygen:
9.2 - 11.2 mg/L
Nominal and measured concentrations:
Nominal: 100, 31.6, 10, 3.16 mg/L
Details on test conditions:
TEST SYSTEM
- Test vessel: 5 L glass tank, closed with cover glass
- Aeration: yes
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1


TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: synthetic freshwater according to ISO standard

Reference substance (positive control):
no
Duration:
96 h
Dose descriptor:
LC0
Effect conc.:
31.6 mg/L
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
100 mg/L
Duration:
96 h
Dose descriptor:
other: Geom. Mean
Effect conc.:
56.2 mg/L
Details on results:
The oily product reacted into insoluble white crystals during the stirring phase.
Validity criteria fulfilled:
yes
Conclusions:
The acute fish toxicity of test item was tested following EU Method C.1 (Acute Toxicity for Fish) and resulted in a LC50 (96h) of 56.2 mg/L (Bayer, 1995).
Executive summary:

The acute fish toxicity of 4 -Trifluormethoxyphenylisocyanate was tested following EU Method C.1 (Acute Toxicity for Fish) and resulted in a LC50 (96h) of 56.2 mg/L (Bayer, 1995).

Description of key information

The short-term toxicity of 4-Trifluormethoxyphenylisocyanat to fish resulted in a LC50 of 56.2 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Dose descriptor:
LC50
Effect concentration:
56.2 mg/L

Additional information