Registration Dossier
Registration Dossier
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EC number: 500-004-7 | CAS number: 9003-29-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Dose descriptor:
- NOAEL
- 1 000 mg/kg bw/day
Additional information
In this IUCLID data set two oral repeated dose studies (C20 -C24 and C16/18 olefins), one inhalative
repeated dose study (1 -hexene) and one dermal repeated dose study (C12 -C16 olefin fraction)
are cited and demonstrate the test substances´ low level of toxicity.
Furthermore, similar low levels of toxicity were demonstrated in several rat oral repeated dose studies with
structural analogues of members of the Higher Olefins Category. The substances tested were: C6, C8
and C14 linear alpha olefins, C6 internal olefin (58% branched), C16/C18 internal olefins (26%
branched), C18 internal olefin (32.5% branched) and C20-C24 internal olefins (>70% branched).
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
