Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 601-577-7 | CAS number: 118969-29-2
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 3-[(2E)-2-benzylidenehydrazino]-4-sulfonatobenzoate, disodium salt
- EC Number:
- 601-577-7
- Cas Number:
- 118969-29-2
- Molecular formula:
- C14H10N2Na2O5S
- IUPAC Name:
- 3-[(2E)-2-benzylidenehydrazino]-4-sulfonatobenzoate, disodium salt
- Test material form:
- other: solid
- Details on test material:
- Purity 59.2%
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Type of coverage:
- occlusive
- Preparation of test site:
- shaved
- Vehicle:
- water
- Duration of treatment / exposure:
- 4 h
- Observation period:
- 1,24,48,72 h
- Number of animals:
- 3
Results and discussion
Any other information on results incl. tables
Under the experimental conditions employed FAT 92334/A induced erythema and edema reactions when applied to the clipped albino rabbit skin. Because the mean values of the recordings 24 to 72 hours after application are below the threshold of significance (2 score for erythema or edema) FAT 92334/A can be classified as non-irritant according to the Commission Directive 83/467/EEC.
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: other: 83/467/EEC
- Conclusions:
- not irritating
- Executive summary:
No adverse effect observed (not irritating)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
