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EC number: 443-050-2 | CAS number: 120903-40-4 PERFLUOROHEXANE NITRILE VINYL ETHER
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
72 hour EC50 >2.5 mg/L (time weighted average) in Pseudokichneriella subcapitata (OECD 201).
72 hour EC10=1.8 mg/L (time weighted avearge) in Pseudokichneriella subcapitata (OECD 201).
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 2.5 mg/L
- EC10 or NOEC for freshwater algae:
- 1.8 mg/L
Additional information
MV5CN s is both volatile and hydrolytically unstable. As such, to
the extent that the test material remains in water the effects are due
to the hydrolysis product. Thus, the key study was conducted using the
hydrolysis product. MV5CN amide is the hydrolysis product of MV5CN. The 72 hour EC50 and EC10 of MV5CN amide to Pseudokichneriella subcapitata were determined in a test run according to OECD 201 guidelines. Concentrations of 0.32, 1.0, 3.2, 10, 32, and 100 % of a saturated solution made at a 100 mg/L loading rate, were tested and the measured time-weighted average concentrations were 0.016, 0.046, 0.14, 0.48, 1.2 and 2.5 mg/L. No dispersants were used. An EC50 > 2.5 mg/L (time weighted average) and an EC10=1.8 mg/L (time weighted average) were determined. There was 16% inhibition of growth rate and 60% inhibition of yield at the highest concentration tested.
Study was conducted under international guidelines and was compliant with GLP criteria. Therefore, this study is considered reliable without restrictions. The result is considered suitable for use in Risk Assessment, Classification & Labeling, and PBT analysis.
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