Registration Dossier
Registration Dossier
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EC number: 248-688-3 | CAS number: 27841-06-1
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The PBT Assessment for Neopentyl glycol dicaprate (CAS No. 27841-06-1) is based on the criteria set out in the “Guidance on information requirements and chemical safety assessment, Chapter R.11: PBT Assessment” (ECHA, 2017).
Persistence Assessment
Neopentyl glycol dicaprate (CAS No. 27841-06-1) is considered readily biodegradable according to OECD criteria based on read-across data. Thus, the substance does not meet the screening criterion for persistence and is not considered to be P or vP.
Bioaccumulation Assessment
Neopentyl glycol dicaprate (CAS No. 27841-06-1) is readily biodegradable and therefore considered to be not P or vP. Therefore, no B-assessment was carried out since it is only required if the substance fulfills the P or vP criteria, according to the guideline (Guidance on Information Requirements and Chemical Safety Assessment Chapter R.11: PBT/vPvB assessment, 2017).
Toxicity Assessment
For Neopentyl glycol dicaprate (CAS No. 27841-06-1), the available acute effect concentrations (fish, aquatic invertebrates, algae) are > 0.086 mg/L, which is above the water solubility(< 2.4 µg/L at 20 °C, pH 6.3; OECD 105, column elution method). The chronic effect concentrations (daphnia, algae) are≥0.0019 mg/L. The substance is not classified as carcinogenic (category 1A or 1B), germ cell mutagenic (category 1A or 1B) or toxic for reproduction (category 1A, 1B or 2) according to Regulation (EC) No 1272/2008. In addition, the substance shows no specific target organ toxicity after repeated exposure (STOT RE category 1 or 2) according to Regulation (EC) No 1272/2008. The substance is readily biodegradable, indicating no persistence. Therefore, the criteria set out in Annex X of Regulation (EC) No 1907/2006 are not met and the test substance is not considered to meet the T criterion.
Conclusion
In conclusion, the substance is not PBT/vPvB.
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