Reaction mass of 1,1,2,2,3,3,3-heptafluoro-N-(heptafluoropropyl)-N-(pentafluoroethyl)propan-1-amine and 1,1,2,2,3,3,3-heptafluoro-N-(heptafluoropropyl)-N-(trifluoromethyl)propan-1-amine and 1,1,2,2,3,3,3-heptafluoro-N,N-bis(heptafluoropropyl)propan-1-amine

Boiling point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

11-Dec-2017 to 21-Dec-2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 0002712253
- Physical state: colorless, clear liquid
- Expiration date of the lot/batch: 07 June 2020
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: at room temperature
- Stability under test conditions: test substance stable, but extremely volatile

Key result

Boiling pt.:

83.2 °C

Atm. press.:

1 002 hPa

Decomposition:

no

The DSC-curve obtained with Experiment 1 is shown in Figure 1. During cooling, no effects were observed. During heating, an endothermic peak between 0 °C and 125 °C was observed. The extrapolated onset temperature of the peak was 66.601 °C. The endothermic effect was most likely obtained due to boiling of the test substance. After the experiment it was observed that the test substance had evaporated from the sample container. A higher heating rate of 50 °C/minute was applied in Experiment 2 to investiage the endothermic peak. The extrapolated onset temperature of the endothermic peak in Experiment 2 was 89.024 °C. The endothermic peak had not shifted significantly to higher temperatures, but the width of the peak differed between the experiments as a consequence of the temperature ramp applied. After the experiment, it was observed that the test item had evaporated from the sample container. Experiment 3 was performed as a duplicate of Experiment 1, but without a cooling cycle. The result is similar to what was found in Experiment 1. The extrapolated onset of the boiling peak was 83.036 °C. After the experiment, it was observed that the test item might have been evaporated from the sample container. Experiment 4 was performed as a duplicate of Experiment 3. After the experiment, it was observed that the test item had evaporated from the sample container. The boiling temperature was determined as the mean boiling temperature of Experiment 3 (83.332°C) and Experiment 4 (83.036°C).

Conclusions:

The boiling point of MTDID 50908 was determined as 83.2 °C at 1002 hPa, as determined by EU Method A.2.

Executive summary:

The boiling point of MTDID 50908 was tested using differential scanning calorimetry (DSC) in four experiments. The boiling point was determined as 83.2 °C at 1002 hPa. The boiling temperature was determined as the mean evaporation temperature of two trials done under comparable conditions. The study was conducted in accordance with EU Method A.2 and was GLP compliant; therefore the study is considered reliable without restrictions.

Reference 2

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

19 July 2017

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

other: ASTM D1120-94 “Standard Test Method for Boiling Point of Engine Coolants"

Deviations:

no

GLP compliance:

no

Type of method:

dynamic method

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: ZF-0002-1545-7 Lot Number 040088

Key result

Boiling pt.:

94.4 °C

Atm. press.:

760 mm Hg

Decomposition:

no

Temp (°C)	Vapor Pressure (mm Hg)
48.6	147.2
66.3	296.5
74.7	394.0
81.3	494.9
86.9	597.2
93.3	736.2

ln(Pvap) = -4230.127196/(T (°C) + 273.15)  + 18.14245

R2=0.999884

Conclusions:

The boiling point of MTDID 50908 is 94.4 °C at 760 mm Hg.

Executive summary:

A boiling point of 94.4 °C at 760 mm Hg for MTDID 50908 was extrapolated from data measured for the compound using the dynamic method. The vapor pressure and temperature were recorded at a variety of equilibrium points from 48.6 °C to 93.3 °C. The study was conducted following method ASTM D1120-94 but was not conducted in accord with GLP guidelines; therefore, the study is considered reliable with restrictions.

Reference 3

Endpoint:

boiling point

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods with acceptable restrictions

Remarks:

The boiling point was obtained using an internal method which is similar to ASTM D1120-65 - Standard Test Method for Boiling Point of Engine Coolants. Documentation of the experimental measurement is not available.

Qualifier:

equivalent or similar to guideline

Guideline:

other: ASTM D1120-65

Version / remarks:

The result was obtained using an internal method, which cites ASTM D1120-65.

GLP compliance:

not specified

Type of method:

ebulliometer

Specific details on test material used for the study:

Lot No: 040088
Manufacture Date: 23-Apr-2015

Key result

Boiling pt.:

94.9 °C

Atm. press.:

760 mm Hg

Conclusions:

MTDID 50908 has a boiling point of 94.9°C at 760 mm Hg.

Executive summary:

MTDID 50908 has a boiling point of 94.9°C at 760 mm Hg. The boiling point cited an internal method, which is similar to ATSM D1120-65. The boiling point is measured at a monitored barometric pressure and corrected to an atmospheric pressure of 760 mm Hg. The result is considered reliable with restrictions, and suitable for Risk Assessment, Classification and Labeling.

Reference 4

Endpoint:

boiling point

Type of information:

not specified

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

documentation insufficient for assessment

Qualifier:

no guideline followed

GLP compliance:

not specified

Boiling pt.:

>= 80 - <= 110 °C

Conclusions:

A boiling point range of 80-110 °C was reported for MTDID 50908.

Executive summary:

A boiling point range of 80-110 °C was reported for MTDID 50908. Only the result was reported on the Safety Data Sheet and no information about the pressure or method used were provided; therefore the reliability of the data is not assignable.

Description of key information

The boiling point of MTDID 50908 was determined as 83.2 °C at 1002 hPa according to EU Method A.2.

Additional information

In the key study, the boiling point of MTDID 50908 was determined to be 83.2°C at 1002 hPa, using differential scanning calorimetry (DSC) in four experiments. The boiling temperature was determined as the mean evaporation temperature of two trials done under comparable conditions. The study was conducted in accordance with EU Method A.2 and was GLP compliant; therefore the study is considered reliable without restrictions.

In a supporting study, a boiling point of 94.4 °C at 760 mm Hg for MTDID 50908 was extrapolated from data measured for the compound using the dynamic method. The vapor pressure and temperature were recorded at a variety of equilibrium points from 48.6 °C to 93.3 °C. The study was conducted following method ASTM D1120-94 but was not conducted in accord with GLP guidelines; therefore, the study is considered reliable with restrictions.

Another supporting study reports a boiling point of 94.9°C at 760 mm Hg for MTDID 50908. The boiling point cited an internal method, which is similar to ASTM D1120-65 in which the boiling point is measured at a monitored barometric pressure and corrected to an atmospheric pressure of 760 mm Hg. The result is considered reliable with restrictions.

Additional supporting data is a boiling point range of 80-110 °C, reported for MTDID 50908. Only the result was reported on the Safety Data Sheet and no information about the pressure or method used were provided; therefore the reliability of the data is not assignable.