Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-516-3 | CAS number: 1328-18-3 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 59805.
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1974/75
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
- Principles of method if other than guideline:
- BASF-Test
- GLP compliance:
- no
- Test type:
- other: BASF Method
Test material
- Reference substance name:
- Anthra[9,1,2-cde]benzo[rst]pentaphene-5,10-dione, bromo derivatives
- EC Number:
- 215-516-3
- EC Name:
- Anthra[9,1,2-cde]benzo[rst]pentaphene-5,10-dione, bromo derivatives
- Cas Number:
- 1328-18-3
- Molecular formula:
- C34H14Br2O2
- IUPAC Name:
- anthra[9,1,2-cde]benzo[rst]pentaphene-5,10-dione, bromo derivatives
- Test material form:
- solid
- Details on test material:
- Vat Blue 19
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- no data
Administration / exposure
- Route of administration:
- inhalation: dust
- Type of inhalation exposure:
- not specified
- Vehicle:
- other: unchanged (no vehicle)
- Details on inhalation exposure:
- Inhalation by means of dust enriched vapor for 8 hours. To achieve enrichment, air was fed through an approx. 5 cm deep layer of the product (weak dust development).
- Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- 8 h
- Concentrations:
- enriched atmosphere
- No. of animals per sex per dose:
- 12 rats
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: 7 days
- Frequency of observations and weighing: daily observation, weekly weighing
- Necropsy of survivors performed: yes
- Other examinations performed: clinical signs, gross pathology - Statistics:
- NA
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LC0
- Based on:
- test mat.
- Exp. duration:
- 8 h
- Remarks on result:
- other: no effect at saturation concentration
- Mortality:
- no deaths
- Clinical signs:
- other: no effects
- Body weight:
- no data
- Gross pathology:
- no effects
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- 8 hours inhalation of saturated athmosphere did not lead to any deaths in rats (0/12).
- Executive summary:
In an acute inhalation toxicity study, rats were exposed by inhalation to the test item in a saturated atmosphere for 8 hours. No deaths and no gross pathological signs of toxicity were observed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
