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EC number: 232-178-2 | CAS number: 7789-60-8
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Justification for type of information:
- Estimated data generated using the EPI Suite model developed by the USEPA
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- Prediction done using BCFBAF (v3.00) model
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Phosphorus tribromide
- Molecular formula: Br3P
- Molecular weight: 270.686 g/mol
- Smiles notation: P(Br)(Br)Br
- InChl : 1S/Br3P/c14(2)3
- Substance type: Inorganic
- Physical state: Liquid - Radiolabelling:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- other: Fish
- Route of exposure:
- aqueous
- Test type:
- not specified
- Water / sediment media type:
- natural water: freshwater
- Test temperature:
- 25 deg.C
- Reference substance (positive control):
- not specified
- Key result
- Temp.:
- 25 °C
- Type:
- BCF
- Value:
- 14.79 L/kg
- Basis:
- whole body w.w.
- Calculation basis:
- other: estimated
- Remarks on result:
- other: Non bioaccumulative
- Validity criteria fulfilled:
- not specified
- Conclusions:
- From BCFBAF (v3.00) model of EPI suite the estimated bio concentration factor (BCF) for phosphorus tribromide is 14.79 L/kg wet-wt which does not exceed the bioconcentration threshold of 2000. Thus it is concluded that phosphorus tribromide is not expected to bio accumulate in the aquatic environment.
- Executive summary:
From BCFBAF (v3.00) model of EPI suite the estimated bio concentration factor (BCF) for phosphorus tribromide is 14.79 L/kg wet-wt which does not exceed the bioconcentration threshold of 2000.Thus it is concluded that phosphorus tribromide is not expected to bio accumulate in the aquatic environment.
Reference
BCFBAF Program (v3.01) Results:
==============================
SMILES : BrP(Br)Br
CHEM : Phosphorus tribromide
MOL FOR: Br3 P1
MOL WT : 270.69
--------------------------------- BCFBAF v3.01 --------------------------------
Summary Results:
Log BCF (regression-based estimate): 1.17 (BCF = 14.8 L/kg wet-wt)
Biotransformation Half-Life (days) : 0.0294 (normalized to 10 g fish)
Log BAF (Arnot-Gobas upper trophic): 0.83 (BAF = 6.76 L/kg wet-wt)
Log Kow (experimental): not available from database
Log Kow used by BCF estimates: 2.28
Equation Used to Make BCF estimate:
Log BCF = 0.6598 log Kow - 0.333 + Correction
Correction(s): Value
No Applicable Correction Factors
Estimated Log BCF = 1.170 (BCF = 14.79 L/kg wet-wt)
Description of key information
From BCFBAF (v3.00) model of EPI suite the estimated bio concentration factor (BCF) for phosphorus tribromide is 14.79 L/kg wet-wt which does not exceed the bioconcentration threshold of 2000.Thus it is concluded that phosphorus tribromide is not expected to bio accumulate in the aquatic environment.
Key value for chemical safety assessment
- BCF (aquatic species):
- 14.79 L/kg ww
Additional information
Two predicted data from validated models for Bioaccumulation (BCF) endpoint of Phosphorus tribromide (7789-60-8) were summarized as follows:
First study from BCFBAF (v3.00) model of EPI suite the estimated bio concentration factor (BCF) for phosphorus tribromide is 14.79 L/kg wet-wt which does not exceed the bioconcentration threshold of 2000.Thus it is concluded that phosphorus tribromide is not expected to bio accumulate in the aquatic environment.
Above predicted result supported by Scifinder database which indicate the Bioconcentration factor (BCF) for target chemical phosphorus tribromide was predicted to be 38.9 at pH 1-10 at temperature 25 deg.C.Based on the BCF concentration at all range of pH it is concluded that the test chemical phosphorus tribromide is non bioaccumulative in nature as it does not exceed the BCF criteria of 2000.
Both results showed the BCF factor is in the range of 14.79 - 38.9 (L/kg wet-wt or dimensionless) which indicate that the test substance Phosphorus tribromide (7789-60-8) was not expected to bio accumulate in the aquatic environment.
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