Registration Dossier
Registration Dossier
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EC number: 603-330-9 | CAS number: 129332-29-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 29 November 2001-25 March 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.3 (Algal Inhibition test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 00945
- IUPAC Name:
- 00945
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- yes
Test organisms
- Test organisms (species):
- Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 72 h
Test conditions
- Reference substance (positive control):
- yes
- Remarks:
- Test medium without test substance or other additives (blank)
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Any other information on results incl. tables
No inhibition of cell growth or reduction of growth rate was recorded at the maximum soluble test substance concentration in test medium, corresponding to 0.045 -0.080 mg/L (NOEC). Hence, the EC50 for inhibition of algal cell growth and reduction of growth rate exceeded the maximum solubility limit in the test medium. Due to the limited solubility of the test substance in water, concentration levels that might be toxic for algae could not be reached.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Based on the results of the study report, the test substance will not be classified with respect to possible harm for aquatic organisms according to the EEC-directive 98/98. IC50 > 100mg/L
- Executive summary:
Based on the results of the study report, the test substance will not be classified with respect to possible harm for aquatic organisms according to the EEC-directive 98/98. IC50 > 100mg/L
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