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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Peer reviewed journal
Justification for type of information:
Data is from Peer reviewed journal .
Qualifier:
according to guideline
Guideline:
other: refer below principle
Principles of method if other than guideline:
study was conducted to determine long- term toxicity of test chemical to Daphnia magna.
GLP compliance:
no
Analytical monitoring:
no
Test organisms (species):
Daphnia magna
Details on test organisms:
- Common name: Water Flea
- Age of parental stock: 24 hours old
Test type:
flow-through
Water media type:
freshwater
Total exposure duration:
21 d
Duration:
21 d
Dose descriptor:
other: EC20
Effect conc.:
< 1.1 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
immobilisation
Remarks on result:
other: No other details available
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
19.5 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
immobilisation
Remarks on result:
other: No other details available
Details on results:
The study concludes that, 21 days EC20 and EC50 values based on immobilasation was determined to be <1.1 and 19.5 mg/l, respectively.
Validity criteria fulfilled:
not specified
Conclusions:
The study concludes that, 21 days EC20 and EC50 values based on immobilasation was determined to be <1.1 and 19.5 mg/l, respectively.
Executive summary:

The study was conducted to determine the toxic effect of test chemical on the immobilization of fresh water Daphnia magna. The test conducted in flow-through system for 21 days. The 21 days  EC20 and EC50 values based on immobilasation was determined to be <1.1 and  19.5 mg/l, respectively.

Description of key information

The study was conducted to evaluate adverse effects caused by the test chemical on reproduction rate of fresh water flea (Daphnia magna). The 28 days, chronic NOEC value of test substance was concluded  to be <1.1 mg/l.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
1.1 mg/L

Additional information

Following different studies includes estimated study for the target chemical  to observe the blong-term toxicity test chemical to aquatic invertebrates.

The first study was conducted to evaluate adverse effects caused by the test chemical on reproduction rate of fresh water flea (Daphnia magna). Test chemcial was exposed for the period 28 days and young daphnids aged less than 12 hours were used. After the exposure period at 20°C, No observed effect concentration was observed to be <1.1 mg/L.

The second study was conducted to determine the toxic effect of test chemical on the immobilization of fresh water Daphnia magna. The test conducted in flow-through system for 21 days. The 21 days  EC20 and EC50 values based on immobilasation was determined to be <1.1 and  19.5 mg/l, respectively.

The second study was conducted to evaluate the toxicity of test chemical on freshwater crustacean Asellus aquaticus. The EC50 value for test chemical was observed to be 333 mg/L.