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EC number: 619-738-5
CAS number: 87305-03-1
The incidence of rudimentary extra ribs #
14 was significantly increased in dosed group 50.5% compared to 0.66% in
is apparent that pups with extra ribs have markedly lower body weights
than the ones without.
has been demonstrated that extra ribs in rats and mice teratology
studies are associated with a foetal retardation and are indicative of
maternal/foetal toxicity and not a developmental malformation
foetal retardation can also be seen in delayed ossification of other
skeletal elements and the presence of dumbball shaped vertebrae.
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