Registration Dossier
Registration Dossier
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EC number: 500-241-6 | CAS number: 69011-36-5 1 - 2.5 moles ethoxylated
Endpoint summary
Administrative data
Description of key information
Additional information
The chronic toxicity of Isotridecanol, ethoxylated, < 2.5 EO to terrestrial macroorganisms was investigated in a study following OECD 222. Mortality, changes on body weight and the reproduction rate of Eisenia fetida was recorded during a study period of 56 days. Based on the reproduction rate a NOEC (56 d) of 125 mg/kg soil dw (nominal) was recorded.
The toxicity of Isotridecanol, ethoxylated, < 2.5 EO to terrestrial plants was assessed using read-across data for the structurally analogue substance Isotridecanol, ethoxylated 3EO according to OECD guideline 208 and GLP. The study investigated the effect of the test substance on the emergence and growth of three plant species. The tested plant species were wheat, Triticum aestivum, a monocot and the dicots Brassica alba and Lepidum sativum (white mustard and garden cress). In a first test soil was mixed with a stock solution of the test substance to give a nominal exposure concentration of 100 mg/kg soil dw. The seedling emergence was followed for 17 days. At test termination, the plants were harvested and the growth was determined by measuring the weight of the above ground plant parts. Effects on plant growth were only observed for Lepidum sativum. Therefore a second test was performed investigating the growth of Lepidum sativum at test concentrations of 1, 10 and 100 mg/kg soil. An inhibition of plant growth were observed at 100 mg/kg soil dw. An EC0 (17 d)of10 mg/kg soil dw based on plant growth was recorded.
Isotridecanol, ethoxylated, < 2.5 EO is rapidly biodegraded and a rapid mineralisation in aquatic as well as terrestrial environment can be expected and persistence of the substance in the environment is unlikely. The calculated PEC/PNEC ratios for the terrestrial compartment was < 1 for all uses. In conclusion, the environmental exposure assessment for the substance indicates no risk for the terrestrial compartment (all RCR < 1; please refer to Chapter 9 and 10 of the Chemical Safety Report for detailed information. In accordance to column 2 of Annex IX, section 9.4 of Regulation (EC) No. 1907/2006, no further tests on the effects of the substance to terrestrial organisms are needed and consequently further testing was omitted.
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