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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
Qualifier:
according to guideline
Guideline:
EU Method C.3 (Algal Inhibition test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2-bromo-2-methylpropionyl bromide
EC Number:
244-017-3
EC Name:
2-bromo-2-methylpropionyl bromide
Cas Number:
20769-85-1
Molecular formula:
C4H6Br2O
IUPAC Name:
2-bromo-2-methylpropanoyl bromide

Sampling and analysis

Analytical monitoring:
yes

Test organisms

Test organisms (species):
Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h

Test conditions

Hardness:
Standard dilution water (according to ISO 14442)
Test temperature:
Maintained at 23°C
pH:
Start : 7.47 - 5.27 (according to 2-bromoisobutyryl bromide concentrations)
End : 7.38 - 5.80
Dissolved oxygen:
Start : 8.2 - 8.5 mg/L
End : 8.3 - 8.6 mg/L
Salinity:
Not stated
Nominal and measured concentrations:
The ratio final/initial concentrations of 2-bromoisobutyryl bromide has been measured. The average of final concentration of 2-bromoisobutyryl bromide was within the designated limit of 80% of the average of initial concentrations.
Reference substance (positive control):
yes

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
>= 22.7 - <= 50 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
biomass
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
22.7 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
biomass
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
>= 22.7 - <= 50 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
growth rate

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Experimental tests show a minimum of inhibition concentration EC50 of 22.7 mg/L of 2-bromoisobutyryl bromide on algae.
Thus, 2-bromoisobutyryl bromide has to be considered as Harmful to aquatic life (aquatic acute toxicity 3).