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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Qualifier:
according to guideline
Guideline:
EU Method C.2 (Acute Toxicity for Daphnia)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2-bromo-2-methylpropionyl bromide
EC Number:
244-017-3
EC Name:
2-bromo-2-methylpropionyl bromide
Cas Number:
20769-85-1
Molecular formula:
C4H6Br2O
IUPAC Name:
2-bromo-2-methylpropanoyl bromide

Sampling and analysis

Analytical monitoring:
yes

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h

Test conditions

Hardness:
Standard dilution water (according to ISO 6341)
Test temperature:
Beetween 18.6 and 20.6 °C
pH:
Start : 7.78 - 3.98 (according to 2-bromoisobutyryl bromide concentrations)
End : 7.75 - 3.45
Dissolved oxygen:
Start : 8.1 - 8.7 mg/L
End : 8.2 - 8.8 mg/L
Salinity:
Not stated
Nominal and measured concentrations:
The ratio final/initial concentrations of 2-bromoisobutyryl bromide has been measured. The average of final concentration of 2-bromoisobutyryl bromide was within the designated limit of 80% of the average of initial concentrations.
Reference substance (positive control):
no

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
>= 51 - <= 71.4 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: Confident interval 95% not determinated
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
>= 51 - <= 71.4 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: Confident interval 95% not determinated

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Experimental tests show a minimum of immobilisation concentration EC50-48h of 51 mg/L of 2-bromoisobutyryle bromide on daphnia.
Thus, 2-bromoisobutyryle bromide has to be considered Harmful to aquatic life (aquatic acute toxicity 3).