Fatty acids, tall-oil, reaction products with 2-[(2-aminoethyl)amino]ethanol

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2012-05-30 to 2012-12-06

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study has been performed according to OECD guideline 104 and EU method A.4 in a GLP certified testing facility.

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

yes

Remarks:

(lnstead of screw-caps, crimp-caps were used to close the Knudsen cells. The deviation was assessed as uncritical as crimp-caps close the cells more tightly.)

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

yes

Remarks:

(lnstead of screw-caps, crimp-caps were used to close the Knudsen cells. The deviation was assessed as uncritical as crimp-caps close the cells more tightly.)

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: by loss of weight or by trapping vaporisate

Key result

Temp.:

25 °C

Vapour pressure:

0 Pa

Key result

Temp.:

20 °C

Vapour pressure:

0 Pa

Key result

Transition / decomposition:

no

Experiments 1, 2 and 4 (nominal temperatures of 30, 45 and 75 °C) showed no significant weight and/or no reproducible loss. Experiment 3 (nominal temperature of 60 °C) showed a significant weight loss, but no second temperature in the range of 30 - 75 °C which could be used for evaluation. lt was considered that the weight loss at 60°C was caused by minor impurities of the test item. Therefore, experiments 1-4 were not included in the evaluation. All measurement data from experiments 5-9 (at temperatures of 90, 105, 120, 135, and 150 °C) was included in the evaluation as significant and reproducible weight loss was observed.

Upon inspection of the cells after the third measurement series at 150 °C, it was observed that the test item began to change its colour to reddish. Therefore, the cells were not weighed after the third measurement series at 150 °C and the test was finished.

Conclusions:

The vapour pressure of 400112 was determined following EU A.4 and OECD guideline 104 using the effusion method (weight loss).
Based on the regression equation the vapour pressures at 20°C and at 25 °C were calculated for the test item 400112:
Vapour pressure at 20°C: 5.67 * 10E-06 Pa
Vapour pressure at 25°C: 1.07 * 10E-05 Pa

Executive summary:

The vapour pressure of 400112 was examined in nine different experiments using the effusion method (weight loss) with temperatures ranging from 30 to 150°C. The measurements at 30, 45, and 75°C showed no significant and/or no reproducible weight loss. The measurements at 60°C showed a significant weight loss, but no second temperature in the range of 30 - 75°C which could be used for evaluation. lt was considered that the weight loss at 60°C was caused by minor impurities of the test item. Therefore, experiments 1 - 4 were not included in the evaluation. At temperatures between 90 and 150°C (experiments 5 -9) a reproducible weight loss could be measured. For these temperatures, 1/T was plotted against log (P). The graph 1/T vs. log (P) shows a good correlation (r² = 0.9990). Based on the regression equation the vapour pressures at 20°C and at 25°C were calculated for the test item 400112.

Vapour pressure at 20°C: 5.67 * 10E-06 Pa

Vapour pressure at 25°C: 1.07 * 10E-05 Pa

All measured values of the five evaluated experiments show good reproducibility, giving relative standard deviations of less than 20%, and good correlation. The result of the test can be considered valid.

Description of key information

The vapour pressure of 400112 was determined following EU A.4 and OECD guideline 104 using the effusion method (weight loss). Based on the regression equation the vapour pressures at 20°C and at 25 °C were calculated for the test item 400112: 
Vapour pressure at 20°C: 5.67 * 10E-06 Pa 
Vapour pressure at 25°C: 1.07 * 10E-05 Pa

Key value for chemical safety assessment

Vapour pressure:

0 Pa

at the temperature of:

20 °C

Additional information

The vapour pressure of 400112 was examined in nine different experiments using the effusion method (weight loss) with temperatures ranging from 30 to 150°C. The measurements at 30, 45, and 75°C showed no significant and/or no reproducible weight loss. The measurements at 60°C showed a significant weight loss, but no second temperature in the range of 30 - 75°C which could be used for evaluation. lt was considered that the weight loss at 60°C was caused by minor impurities of the test item. Therefore, experiments 1 - 4 were not included in the evaluation. At temperatures between 90 and 150°C (experiments 5 - 9) a reproducible weight loss could be measured. For these temperatures, 1/T was plotted against log (P). The graph 1/T vs. log (P) shows a good correlation (r² = 0.9990). Based on the regression equation the vapour pressures at 20°C and at 25°C were calculated for the test item 400112.

Vapour pressure at 20°C: 5.67 * 10E-06 Pa

Vapour pressure at 25°C: 1.07 * 10E-05 Pa

All measured values of the five evaluated experiments show good reproducibility, giving relative standard deviations of less than 20%, and good correlation. The result of the test can be considered valid.