Registration Dossier
Registration Dossier
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EC number: 249-277-1 | CAS number: 28874-51-3
Vapour pressure
Administrative data
Link to relevant study record(s)
Description of key information
Vapour pressure = 0.54 kPa at 20 °C and 0.68 kPa at 25 °C, OECD 104, EU Method A. 4, Sárvári 2012c.
Key value for chemical safety assessment
- Vapour pressure:
- 0.54 kPa
- at the temperature of:
- 20 °C
Additional information
The key study (Sárvári, 2012c) was performed under GLP conditions and in accordance with standardised guidelines. The study was assigned a reliability score of 1 in line with the principles for assessing data quality as defined by Klimisch (1997). Under the conditions of the study, the vapour pressure of the test material was determined to be 0.54 kPa at 20 °C and 0.68 kPa at 25 °C.
The supporting study (Atwall, 2008) was performed using the read across substance, sodium 5-oxo-DL-prolinate, which is a racemic mixture of the D- and L- isomeric forms of the substance. Read-across is considered to be suitable based on the structural similarities between the read across substance (sodium 5-oxo-DL-prolinate) and the substance to be registered (sodium 5-oxo-L-prolinate), which is the L- isomer only. As such the difference in isomeric forms of the substance is unlikely to affect the physico-chemical properties. The study was conducted under GLP conditions and in accordance with standardised guidelines. The study was assigned a reliability score of 2 in line with the principles for assessing data quality as defined by Klimisch (1997). Under the conditions of the study, the vapour pressure was determined to be < 8.4 x 10^-4 at 25 °C, calculated using regression analysis.
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