Registration Dossier
Registration Dossier
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EC number: 443-940-0 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
A study was conducted to assess the sensitizing potential of the test substance in female guinea pigs (Magnusson & Kligman method) according EU Method B.6., OECD guideline 406 and OPPTS 870.2400.
Intradermal induction was performed using 5 % test substance in sesame oil. Dermal induction and challenge treatment were carried out with 25 % test substance in deionised water.
The validity of the test system is confirmed by the periodically conducted positive control test using alpha-hexyl cinnamic aldehyde for the Buehler test.
The test substance showed no evidence for sensitizing properties in guinea pigs (Dr. Ehling G, 2002).
Migrated from Short description of key information:
The test substance showed no evidence for sensitizing properties in guinea pigs.
Justification for classification or non-classification
The test substance was negative in in vivo skin sensitisation test and therefore no classification is required for sensitisation according to EC criteria (67/548/EEC) and CLP criteria (EC 1272/2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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