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Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
24 February - 12 March 2004
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
Version / remarks:
May 1981
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Key result
Medium:
standard fat
Solubility:
< 0.151 other: mg/100g fat
Temp.:
37 °C
Details on results:
For details see attachment "T-1063FM - results fat solubility.pdf".
Conclusions:
The high fat solubility value of the preliminary test is due to the supersaturated solution.
The solubility of the test substance in standard fat simulant HB 307 is <0.151 mg/100 g (at 37 °C).

Description of key information

< 0.15 mg/100g  (OECD guideline 116)

Key value for chemical safety assessment

Additional information

The solubility of the test substance in standard fat simulant HB 307 is <0.151 mg/100 g (at 37 °C).