Registration Dossier
Registration Dossier
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EC number: 260-252-4 | CAS number: 56539-66-3
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- GLP compliance:
- yes
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- gas chromatography
- Type:
- log Pow
- Partition coefficient:
- 0.18
- Temp.:
- 24.8 °C
- pH:
- 6.4
- Conclusions:
- In conclusion, the log octanol/water partition coefficient value of 0.18 at 24.8°C and pH 6.3 was obtained for 3-methoxy-3-methylbutan-1-ol using the shake-flask method.
Reference
Results of the measurement of partition coefficient
| POW=CO/CW | log POW | |||||
| Measured value | Mean value | Total mean value | ||||
| Measured condition 1 | a | 1.50 | 0.18 | 0.17 | 0.18 Standard deviation = 0.016Maximum difference = 0.03 | |
| b | 1.48 | 0.17 | ||||
| Measured condition 2 | a | 1.57 | 0.20 | 0.19 | ||
| b | 1.50 | 0.17 | ||||
| Measured condition 3 | a | 1.60 | 0.20 | 0.19 | ||
| b | 1.47 | 0.17 | ||||
Results of pH measurement of water phase
| Measurement value | ||
| Sample a | Sample b | |
| Measured condition 1 | 6.6 | 6.3 |
| Measured condition 2 | 6.5 | 6.3 |
| Measured condition 3 | 6.4 | 6.3 |
Description of key information
Log Kow: 0.18 at 25°C
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 0.18
- at the temperature of:
- 25 °C
Additional information
A partition coefficient Octanol/Water Log Kow = 0.18 at 24.8°C was reported in a reliable study, conducted according to an appropriate test protocol.
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