Registration Dossier
Registration Dossier
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EC number: 481-830-4 | CAS number: 3687-22-7
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (LLNA)
- Type of information:
- other: SNIF
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- other: SNIF#001-4.1.70-01
- Title:
- Unnamed
- Year:
- 2 008
- Reference Type:
- other: body responsible for test
- Title:
- Unnamed
- Year:
- 2 008
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- SNIF
- GLP compliance:
- not specified
- Type of study:
- mouse local lymph node assay (LLNA)
Test material
Constituent 1
In vivo test system
Test animals
- Species:
- mouse
- Strain:
- CBA
- Sex:
- male/female
Study design: in vivo (LLNA)
- Vehicle:
- acetone/olive oil (4:1 v/v)
- No. of animals per dose:
- 5 groups of 4 female, CBA strain mice were treated with test substance
Results and discussion
In vivo (LLNA)
Results
- Parameter:
- SI
- Value:
- 25
Any other information on results incl. tables
Results: Positive
Positive control:
alpha-hexylcinnamic aldehyde in acetone/olive oil (4:1) at 25% % S.I 25 6.83
Applicant's summary and conclusion
- Interpretation of results:
- sensitising
- Remarks:
- Migrated information
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